The diagnostic value of EUS-FNA for biopsy of paraesophageal mass

Abstract

Objective To evaluate the diagnostic value of EUS-FNA for paraesophageal mass. Methods Data of a total of 115 consecutive patients with mass in lungs or mediastinum who underwent EUS-FNA from February 2010 to February 2015 were retrospectively analysed. Results One hundred and four patients (90.4%) obtained a definite diagnosis (including 10 cases of histological confirmation and 7 case of cytological confirmation), and 87 cases were diagnosed with histology and cytology, which were consistent. The final diagnoses were 57 thoracic tumors, 31 metastatic mediastinal lymph nodes from other malignant tumors which were non-lung-cancer, and 16 mediastinum benign diseases. In addition to metastatic thoracic tumors to mediastinal lymph nodes such as lung cancer or esophageal cancer, 11 metastatic abdominal malignant tumors to mediastinal lymph nodes, and 7 metastatic thoracic malignant tumor to abdominal lymph nodes, and 1 metastatic nasopharyngeal carcinoma to mediastinal and abdominal lymph nodes, and 3 metastatic mediastinal lymph nodes with uncertain origins. Conclusion EUS-FNA is of significant clinical value for diagnosing origins of paraesophageal masses, and distant metastatic pulmonary and abdominal tumors because of simultaneous tests and puncture at multiple sites of thorax and abdomen. Key words: Tumor; Lung; Lymph node; Mediastinum; Diagnosis; Endoscopic ultrasound-guided fine needle aspiration