The diagnostic value of endoscopic ultrasonography guided fine needle aspiration for occupying pancreatic lesions

Abstract

Objective To evaluate safety and efficacy of EUS-FNA for occupying pancreatic lesions. Methods Data of 62 patients with occupying pancreatic lesions, who underwent EUS-FNA between June 2011 and June 2014, were analyzed for completion and complications, with surgery and clinical follow-up as the golden standard. Accuracy, sensitivity and specificity of EUS-FNA were calculated. Results A total of 62 patients with pancreatic lesions successfully underwent EUS-FNA and median puncture number was 4.2(3 to 8). Success rate of puncture was 100% and sampling satisfaction rate was 90.3%(56/62). No complications such as fever, infection, bleeding, perforation, severe pancreatitis or death were found. With the final diagnosis as the golden standard(39 malignant lesions and 23 benign lesions), overall diagnostic accuracy of EUS-FNA was 88.7%(55/62). The cytology diagnostic accuracy was 69.4%(43/62), significantly higher than that of the tissue pathology of 30.6%(19/62, P<0.01). Sensitivity and specificity of the procedure were 87.2%(34/39) and 91.3%(21/23) respectively. Conclusion EUS-FNA is an effective and safe procedure in diagnosis of occupying pancreatic lesions. Key words: Ultrasonography; Pancreatic diseases; Cytopathology; Histopathology; Fine needle aspiration