The diagnostic significance of EPS inflammatory factors combined with procallcitonin in bacterial prostatitis

Abstract

Objectives To explore the diagnostic significance of EPS inflammatory factors combined with procallcitonin in the diagnosis of bacterial prostatitis. Methods 380 cases of patients with prostatitis in our hospital from January 2012 to December 2014 were selected as study objects. Urine and EPS were cultured. The patients were divided into three types, type Ⅱ(n=61) , type Ⅲa (n=235), type Ⅲb (n=84) by NIH-CPSI score. 20 cases of normal patients were selected as controls. IL-1β, IL-8, TNF-α, PGE2 and PCT levels were measured by radioimmunoassay. The levels of EPS inflammatory factors and serum PCT in each group were compared, the levels of EPS inflammatory factors and serum PCT were then applied for diagnosis to evaluate its diagnostic value. Results The levels of EPS inflammatory factors in type Ⅱgroup were significant higher than in type Ⅲa, type Ⅲb and control groups(P<0.05). The levels of PCT in type Ⅱgroup were significant higher than in the other three groups(P<0.05). The diagnostic accuracy of combined diagnosis was 96.67%, it was significant higher than diagnosis with EPS inflammatory factors alone (P<0.05). Conclusions Combined determination of EPS inflammatory factors with PCT could provide references for diagnosis and differentiation of prostatitis. Key words: Prostatitis; Calcitonin