Abstract
This research aims to study levels of fetal hemoglobin and blood oxygen saturation in 264 patients with chronic diffuse liver diseases, among them 69 patients with chronic hepatitis and 195 patients with liver cirrhosis. To determine the levels of fetal hemoglobin, a patented method of rocket electrophoresis in agar gel with sodium dodecyl sulfate was used. The level of fetal hemoglobin in liver cirrhosis were significantly increased compared to chronic hepatitis, and, in both cases, compared with the control group. Oxygen saturation of the blood was reduced mainly in liver cirrhosis. In patients with liver cirrhosis a relationship between fetal hemoglobin and oxygen saturation was established. Our study helps in the early diagnosis of latent chronic hypoxia and hypoxemia in patients with liver disease. This allows to assess disease severity and adjust the treatment
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