The diagnosis and treatment of adrenal ganglioneuroma

Abstract

Objectives To discuss the diagnosis and treatment of adrenal ganglioneuroma.Methods Twenty-five cases of adrenal ganglioneuroma at our hospital from August 1998 to April 2011 were reviewed.Their clinical manifestation,physical signs,the auxiliary examination,pathological characteristics,diagnosis and differential diagnosis and treatment as well as follow-up data were analyzed retrospectively.Results Here were 10 males and 15 females with all age range of 3 ～ 63 (33.5 ± 15.3) years old.The range of tumor diameter is 1.5 ～ 10.2 cm and the average is (6.2 ± 1.6) cm.The presenting symptoms and signs of the patients were back pain(n =3,12.0％),dizziness,headache,chest tightness and heart palpitations (n =5,20.0％),hypertension (n =7,28.0％),and 5 cases left,twenty cases right.24 case were diagnosis Adrenal Ganglioneuromas Preoperatively after operation.And 1 case was diagnosis Adrenal Ganglioneuromas and adrenal pheochromocytoma.Among all cases,either open operation (n =16) or retroperitoneal laparoscopic excision (n =9) was performed successfully.No recurrence was detected after a follow-up period of 1 ～ 14 years,but 1 case lost to follow-up.Conclusions Adrenal Ganglioneuromas is often found incidentally without specific clinic symptoms.The Diagnosis of Adrenal Ganglioneuromas is mainly based on imaging examination,and postoperative pathology.The Surgical resection of Adrenal Ganglioneuromas is good. Key words: Adrenal tumor; Neoplasms; Neuroma