Abstract

The aim. Determine the effect on the organism, including the oral mucosa, by high-fat nutrition using palm oil and butter.The materials and methods. Rats received high-fat diets (HFD) with the introduction of 20 % palm or butter for 60 days. Controls were rats fed a fat-free diet (FFD). We determined the weight gain of animals, the level of glu-cose, triglycerides (TG), serum cholesterol and the level of elastase, urease, lysozyme, catalase and mDA in the oral mucosa (OM).The findings. The daily gain in body weight, glucose, TG and cholesterol levels were higher in rats treated with butter, however, elastase activity in OM was higher in rats treated with palm oil. In rats treated with butter, MDA increased in OM and the activity of lysozyme de-creased.The conclusion. HFD, especially with palm oil, causes the development of stomatitis. HFD with butter has a more negative effect on the organism (in terms of serum glucose, TG, cholesterol, and in OM of MDA and lyso-zyme) than HFD with palm oil.

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