Abstract
Precision medicine allows a dramatic expansion of biological data, while there is still an urgent need to understand and insight the exact meaning of those data to human health and disease. This has led to an increasing wealth of data unanalyzed. The concept of precision medicine is about the customization of healthcare, with decisions and practices tailored to an individual patient based on their intrinsic biology in addition to clinical “signs and symptoms”. Construction of a standardized model for the integration of data from various platforms is the central mission of the ‘New Disease Management Model’. The model is helpful for the development of new taxonomy of diseases and subtypes, to personalize therapy based on patient genetic profiles. A rapid progression of precision therapy has been made recently. Clinical trials have shown the therapeutic efficacy of discovered and developed therapeutic agents has improved. However, next-generation drugs would be designed for disease subtypes with more specificity, efficacy and lower toxicity.
Highlights
Precision medicine allows a dramatic expansion of biological data, while there is still an urgent need to understand and insight the exact meaning of those data to human health and disease
In 2011, national research council of the national academies have published “Toward precision medicine: Building a knowledge network for biomedical research and a new taxonomy of disease”, which suggests that genomic findings promote the integration of information between biomedical research and clinical medicine [1]
With decisions and practices being tailored to the individual patient based their intrinsic biology in addition to traditional physical signs and symptoms [2]
Summary
Precision medicine allows a dramatic expansion of biological data, while there is still an urgent need to understand and insight the exact meaning of those data to human health and disease. Precision medicine aims to harness large amounts of data available from the human genome and the subsequent research wave of the molecular basis of disease. There is a distinct from other similar ideas of personalized medicine, in that precision medicine implies that unique treatments can be designed for each individual, severe taxonomic needs of the biomedical research and medical communities, providing a profound definition of diseases subtypes at the molecular level.
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