Abstract
This is a report on the James L. Waters Symposium at PittCon 2010, which featured four speakers responsible for the development and the commercialization of liquid chromatography-mass spectrometry (LC-MS). • An early pioneer, William McFadden described the development of the moving belt system in the 1970s. • Marvin Vestal, CEO & CSO of Virgin Instruments, described how he and his team designed and perfected thermospray technology in the 1980s. • Jack Henion, Chairman and CSO of Advion BioSciences, Inc., discussed direct liquid introduction (DLI), atmospheric pressure ionization (API), the development of electrospray and new developments (e.g., bench-top LC-MS systems, nanospray, ion traps and microfluidics). • Tom Covey, a principal scientist at AB SCIEX, used the metaphor of the world histomap to document the history of LC-MS and compare his fellow speakers to famous historical figures.
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