Abstract

Delayed-type hypersensitivity (DTH) was demonstrated in malignant catarrhal fever (MCF) virus-infected rabbits intradermally injected with homologous viral antigens. The response was first detected four days post-infection (pi) and was maximal on day 7 pi. DTH could not be demonstrated after the onset of pyrexia. The abrogation of DTH in MCF virus-infected rabbits is discussed in relation to the pathogenesis of the disease.

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