Abstract
Central pontine myel i nolysis is a demyelinating disorder, which is commonly associated with the rapid correction of hyponatremia. We repot an 84-year-old type 1 diabetic woman with high level of anti-insulin antibody, who developed central pontine myelinolysis, in spite of a careful correction of hyponatremia. We believe that high level of anti-insulin antibody and similar clinical manifestations to autoimmune polygrandular syndrome such as Candidiasis, hypothyroidism, type 1 diabetes and liver cirrhosis possibly due to autoimmune hepatitis may be associated with the development of central pontine myelinolysis. doi: http://dx.doi.org/10.4021/jem112w
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