Abstract

A fetal growth chart is a vital tool for assessing fetal risk during pregnancy. Since fetal weight cannot be directly measured, its reliable estimation at different stages of pregnancy has become an essential issue in obstetrics and gynecology and one of the critical elements in developing a fetal growth chart for estimated fetal weight. In Indonesia, however, a reliable model and data for fetal weight estimation remain challenging, and this causes the absence of a standard fetal growth chart in antenatal care practices. This study has reviewed and evaluated the efficacy of the prediction models used to develop the most prominent growth charts for estimated fetal weight. The study also has discussed the potential challenges when such surveillance tools are utilized in low resource settings. The study, then, has proposed an alternative model based only on maternal fundal height to estimate fetal weight. Finally, the study has developed an alternative growth chart and assessed its capability in detecting abnormal patterns of fetal growth during pregnancy. Prospective data from twenty selected primary health centers in South Kalimantan, Indonesia, were used for the proposed model validation, the comparison task, and the alternative growth chart development using both descriptive and inferential statistics. Results show that limited access to individual fetal biometric characteristics and low-quality data on personal maternal and neonatal characteristics make the existing fetal growth charts less applicable in the local setting. The proposed model based only on maternal fundal height has a comparable ability in predicting fetal weight with less error than the existing models. The results have shown that the developed chart based on the proposed model can effectively detect signs of abnormality, between 20 and 41 weeks, among low birth weight babies in the absence of ultrasound. Consequently, the developed chart would improve the quality of fetal risk assessment during pregnancy and reduce the risk of adverse neonatal outcomes.

Highlights

  • Fetal growth is one of the critical indicators for assessing fetal risk during pregnancy

  • The review and evaluation were explicitly focused on the statistical models used to predict fetal weight and the potential challenges when the charts are utilized in Indonesian health care centers where advanced health equipment and facilities are not always available, or necessary

  • Using data recorded between 32 and 42 weeks, the results showed that the proposed quadratic model produced smaller mean prediction error (ME) (154.4g), less mean percentage prediction error (MPE) (3.8%), and less mean absolute percentage prediction error (MAPE) (8.9%)

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Summary

Introduction

Fetal growth is one of the critical indicators for assessing fetal risk during pregnancy. Monitoring the intrauterine development of the fetus at different stages of pregnancy, even at earlier gestational ages (GAs), is vital for early detection of growth abnormalities [4]. In this way, delays in making informed referrals, decisions, and interventions can be minimized to ensure safe delivery and a positive pregnancy outcome, crucial for those who are living in rural areas or settings with limited health resources. Since fetal weight cannot be directly measured, its reliable estimation at different stages of pregnancy has become one of the important issues in obstetrics and gynecology, and one of the key elements in developing a fetal growth chart for the estimated fetal weight (EFW)

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