The development in vivo and in vitro of the lower incisor and molars of the mouse

Abstract

The normal development is described of the lower incisor of the mouse from the eleventh day of foetal life until the sixth day after birth and the development of the first and second molars is briefly outlined. Lower incisor and molar tooth germs were explanted from 13–18 day mouse foetuses and cultivated in vitro. They developed fairly normally until a layer of dentine had been laid down. Differentiation usually stopped at this stage, but in some expiants a little enamel was formed.