The Development and Well-Being Assessment (DAWBA) Screening for Psychiatric Comorbidity in Urban Siberian Adolescents with Functional Gastrointestinal Disorders

Abstract

Introduction: The Development and Well-Being Assessment (DAWBA) diagnostic tool was developed by R. Goodman et al. [1] as comprehensive semistructured interview for the diagnosis of psychiatric disorders and has been found to been an effective diagnostic tool in clinical and epidemiological settings. Data regarding the DAWBA estimated psychiatric symptoms in Russian adolescents with functional gastrointestinal disorders (FGIDs) are limited. Methods: T69 urban Siberian (Krasnoyarsk, Russia) adolescents aged 12-18 attending a tertiary medical center with recurrent abdominal pain were tested with Questionnaire on Pediatric Gastrointestinal Symptoms Rome III Version (QPGS-RIII) questionnaire. The rates of FGIDs in accordance to QPGS-RIII scoring instructions were as follows: functional dyspepsia (FD) - 15, irritable bowel syndrome (IBS) - 34, abdominal migraine - 8, functional abdominal pain - 12. All of them and 95 healthy matched controls (adolescents without recurrent abdominal pain and headache) completed computer-assisted DAWBA package of interviews. Each of psychiatric disorders was coded on a computer-generated 5-point probability scale. Data are shown as Mean (Mean-SE-Mean+SE) of computer-predicted probability. The Mann-Whitney U test is used to compare differences between groups. Results: Significant positive associations were detected between all FGIDs subgroups and obsessivecompulsive disorder with maximal diagnosis probability in abdominal migraine subgroup (Table 1). At the same time, adolescents with abdominal migraine are more prone to have specific phobia. Posttraumatic stress disorder and generalized anxiety disorder were more characteristic for adolescents with IBS, whereas depressive disorder was more typical for FD subgroup.Table 1: Computer-predicted probability of psychiatric disorder generated by the DAWBA in adolescents with with functional gastrointestinal disordersConclusion: Urban Siberian adolescents with FGIDs have a significantly high prevalence of psychiatric comorbidity. Spectrum of psychiatric disorders may be different in FGIDs subtypes that should be taken into account when evaluating the adolescent's mental health status.