Abstract
The fourth-year undergraduate synthetic organic and medicinal chemistry laboratory course at the University of Ottawa was transformed from a traditional laboratory format to a problem-based learning (PBL) format. Authentic problems were developed that closely resembled the types of problems that scientists regularly confront. The development, implementation, and challenges of the fourth-year organic and medicinal chemistry laboratory course taught in PBL format are discussed, as well as results and feedback from the course.
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