Abstract
The formation of N-nitrosodiethanolamine (NDETA) from the reaction of triethanolamine with nitrite has been demonstrated by LIJINSKY et al. (1972) and also by ZINGMARK and RAPPE (1976) under simulated gastric conditions at pH 2-4. Subsequently, FAN et al. (1977) have shown that this reaction occurs in cutting fluids under alkaline conditions, pH 9-11, and have reported levels of NDETA as high as 3%. Little is known of the toxicity of NDETA, but DRUCKREY et al. (1967) have shown that it is carcinogenic in the rat. In order to assess the magnitude of the problem of NDETA contamination in cutting fluids, a limited survey was made of cutting fluids used in Canada.
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