Abstract
Objectives To determine whether feeding CircuCare to rats improves blood circulation, metabolism, immune regulation, endocrine activity, and oxidative stress. Methods 28 eight-week-old male Sprague-Dawley rats were evenly randomized into control and experimental groups. The control group was fed with ordinary drinking water, while the experimental group was fed with CircuCare at a daily dose of 93.75 mg per 300 g of body weight over eight weeks. Both groups were subjected to a swimming test, and blood samples were taken to observe any variations in various biochemical parameters before and after the test. Key Findings. The experimental group's mean swimming exhaustion duration was 53.2% longer and had a significantly higher lactic acid removal ratio. Their mean prostaglandin E2 level and mean glucose, cortisol, and glutathione level (30 minutes after swimming test) were also significantly higher. No undesirable impacts from CircuCare relating to general blood biochemistry values and bone mineral density were reported. Conclusions The present results show that CircuCare can be safely used to increase stamina and exercise capability, expedite the metabolism of lactic acid, accelerate muscle repair, and promote the antioxidant activity of cells in rats.
Highlights
The proper blood flow in the circulatory system is critical to the maintenance of life, as it supplies nutrients to cells throughout the body, in addition to enabling gas exchange, the transport of metabolites, and the maintenance of homeostasis [1]
No significant differences in bone mineral density (BMD), bone volume (BV), Tb.N, Tb.Sp, or Tb.Th were observed between the two groups (Figures 2(a)–2(e))
The related concepts of yin and yang refer to the duality of opposing and complementary and interconnected forces, with traditional Chinese medicine (TCM) theory holding that a balance between the yin and yang qualities within the body is required for good health [22, 23]
Summary
The proper blood flow in the circulatory system is critical to the maintenance of life, as it supplies nutrients to cells throughout the body, in addition to enabling gas exchange, the transport of metabolites, and the maintenance of homeostasis [1]. The causes of insufficient blood circulation include aging, diseases (such as diabetes), unhealthy lifestyle (such as smoking and poor diets), and accidental injuries [2,3,4,5,6]. A variety of symptoms may result from insufficient blood circulation, such as cold extremities, mental exhaustion, and sore and numb limbs. Poor blood circulation can even induce stroke and cardiovascular disease in severe cases [7,8,9,10,11]. Et Maxim.) Harms, Chinese fevervine, Chinese Angelica, Panax ginseng C.A. Meyer, red dates, and licorice. These ingredients are chosen on the basis of the TCM theory regarding the compatibility of “monarch, minister, assistant, and guide” herbs [12]
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