The Detection of Campylobacter pylori (Cp) in Gastro‐Duodenal Disease: The Efficacy of the Rapid Urease (RU) Test and Relationship between Endoscopic Findings, Histological Gastritis and Presence of Cp

Abstract

Abstract: In the comparison of bacteriological and histological methods, the rapid urease (RU) test was considered a specific (100%) method for detection of Campylobacter Pylori (Cp), by which the presence of Cp can be rapidly judged (more than 90% in 20 min.). For an accurate and reliable diagnosis, other methods should be used concurrently, because the sensitivity of this test was inferior to bacteriological methods by 10 to 20%.In the histological study, polymorphonuclear leukocyte infiltration in the antral mucosa clearly reflected Cp infection. This pathological change responded well to antibacterial therapy.Of some endoscopic findings in the gastric antrum, verrucous change was considered to have a relatively close association with Cp infection. However, about 30% of Cp‐present cases had endoscopically no abnormal appearance in the gastric antrum.