Abstract
Lock-in amplifier is widely used to detect weak signals from significant background noise. In this paper, an FPGA-based Lock-in amplifier is implemented on the DSP Builder platform to measure impedance between biological cells and electrodes. To improve the measuring accuracy, a narrow band low pass filter with low cut off frequency was implemented. This low pass filter consists of a five-stage cascaded integrator-comb filter, two half band filters and a FIR low pass filter. Simulation shows that with a system clock of 10MHz, the cut off frequency of the low pass filter is lower than 20Hz. Experiments demonstrate that the implemented lock-in amplifier is able to detect weak signal with strong noise, making it an attractive approach to implement lock-in amplifiers which is more flexible and can meet the needs for specified measurements.
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