The dependence of ultrasonic properties on orientation in human vertebral bone

Abstract

Speed of sound (SOS) and broad-band ultrasound attenuation (BUA) were measured in cubes of human trabecular bone from lumbar vertebrae, in the three major anatomical axes. There were significant differences in SOS and in BUA when measured in the different axes, indicating a structural component to the ultrasonic measurement. Qualitatively different behaviour was observed in the cranio-caudal (CC) axis compared to the transverse directions: SOS was approximately 500 m s-1 greater than in either the lateral (LT) or antero-posterior (AP) axes, and BUA was approximately 23 dB MHz-1 cm-1 greater. Small, but significant, differences existed between the AP and LT axes for both SOS and BUA. In the AP and LT directions, strong linear correlations existed between SOS and apparent density (r=0.90), and between BUA and apparent density (r=0.96). In the CC axis, correlations with density were poorer. The anomalous behaviour in the CC axis was due to a transient travelling ahead of the main wavefront, and it is suggested that this represents propagation of ultrasound directly through the trabecular framework as a bar wave. This can only occur in the CC axis where the majority of trabeculae are orientated parallel to the direction of propagation. Measurements on cubes in air, as opposed to water, supported this hypothesis. Modifications to the experimental technique necessary to consistently detect this phenomenon are described.