Abstract
of relative biological effectiveness of fast neutrons on neutron energy. The first publication (1) in this series dealt with the general considerations that have motivated this work, with the physical aspects of experimental design, and with the measurement of first collision and absorbed doses. The present report3 is concerned with the special techniques required for irradiation of the animals by monoenergetic neutrons and with evaluation of weight changes in spleen and thymus. Subsequent reports will deal with measurements of microscopic distribution of absorbed energy (3, 4) and with other biological results. Work by others (5-9) has indicated relatively low RBE values in small mammals at and above the 10-Mev region, with the suggestion of a rise at lower neutron energies, but with little data obtained below 2 Mev. Therefore, it was desirable to determine RBE values for various criteria in small mammals exposed to monoenergetic neutrons at selected energies in the lower portion of the fast neutron range. (Fast neutrons are defined as those between the energies of 10 kev and 10 Mev in which range most of the dose in tissue is deposited by recoil protons.)
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