Abstract
The definition of lymphocyte activating factor: giving a helping hand to serendipity.
Highlights
A commentary on to Yale I acquired expertise in culturing lymphocytes and Richard (Dick) Gershon, Potentiation of the T-lymphocyte who collaborated with Waksman’s group, response to mitogens
The idea that soluble cell products play (“tolerizing”) doses of sheep red blood important roles in the complex process of cells (RBC) and to test lymphocytes from the immune response was supported by these treated mice for their proliferative scientific evidence in the sixties in sev- responses in culture to the mitogen phyeral publications including those by David tohemagglutinin (PHA) in the presence of et al [1] and Bloom and Bennett [2], sheep RBC
We focused on spleen lymphowho discovered the activity of macrophage cytes of the treated mice, but we exammigration inhibitory factor (MIF), Gor- ined the response of thymus cells of the don and McLean [3] who reported that injected mice
Summary
A commentary on to Yale I acquired expertise in culturing lymphocytes and Richard (Dick) Gershon, Potentiation of the T-lymphocyte who collaborated with Waksman’s group, response to mitogens. I. The responding approached me with the idea to use this cell expertise for studying the activity of the by Gery I, Gershon RK, Waksman BH.
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