Abstract

The default state of the cell: Quiescence or proliferation?

Highlights

  • UBC Envision Group, Southport, CT, USA default state of ‘‘normal cells’’ in somatic mutation theory (SMT), whereas proliferation is assumed as the default state of cells in tissue organization field theory (TOFT) [4]

  • Default state of ‘‘normal cells’’ in SMT, whereas proliferation is assumed as the default state of cells in TOFT [4]

  • It follows from the requirement for growth promotion in the SMT that the default state of the cell is static

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Summary

Introduction

UBC Envision Group, Southport, CT, USA default state of ‘‘normal cells’’ in SMT, whereas proliferation is assumed as the default state of cells in TOFT [4]. It follows from the requirement for growth promotion in the SMT that the default state of the cell is static. It is well established that primary cultured cells from metazoan organisms fail to proliferate in the absence of appropriate growth factors.

Results
Conclusion

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