The Decrease In Number Of Blood Polymorphonuclear (Pmn) To Periapical Radiographs Dose Of radiation exposure

Abstract

Periapical radiograph is a type of radiographic examinations that is widely used in the field of dentistry. Radiographic X-ray is an ionizing radiation that can cause damage and death to cells, tissues or organs, including the polymorphonuclear (PMN). PMN is cell that serves as the first line of defense against the invasion of organisms. Objective: The purpose of this study is 1) to determine whether there is a decrease in the number of peripheral blood PMN after being given periapical radiograph dose of X-ray radiation exposure, and 2) to determine whether there is any difference in the declining number of peripheral blood PMN after being given a single dose and some different total dose of periapical radiograph of X-ray radiation exposure. Methode: The design of this study is an experimental laboratory research with total sample of 24 strains of Balb c male mice. The sample is divided into four groups, each consisting 6 mice. Group 1 serves as the control group; Group 2 is given a treatment with a singledose exposure of periapical radiographs of X-ray radiation; Group 3 is given a treatment of 6 times total doses exposure of periapical radiograph of X-ray radiation; and Group 4 is given a treatment of 14 times total doses exposure of periapical radiograph of X-ray radiation. After 24 hours of radiation exposure, the blood was drown. Conclusion : The calculation is done by multiplying the number of PMN percentage from leukocyte counts with a total leukocyte. The data obtained are statistically tested using One Way Anova and LSD with a significance level of 95%. Result : The result of this study indicates that there is a difference in the peripheral blood PMN counts in male mice after being exposed to radiation doses of periapical radiographs in all groups (P <0.05). There is an increasing number of peripheral blood PMN in male mice after being treatedwith X-ray radiation at a single dose of periapical radiographic exposure, whereas after being exposed with radiation at the dose of 6 and 14,the number of PMN is declining.The highest decreasing number of PMN isfound in the group with exposure of radiation at 14 dose.