Abstract
A man in his 30s presented with a 7-cm left renal mass for which he underwent a radical nephrectomy. Histopathologic examination revealed a neoplasm predominantly composed of spindled cells (Figure 1A, magnification ×40). On higher magnification, these cells had a relatively bland appearance with minimal cytologic atypia and mitotic activity (Figure 1B, magnification ×200). Focal areas of this tumor (<5%) had a tubular component with extravasated mucin (Figure 1C, magnification ×100). Immunohistochemistry showed expression of the transcription factor PAX8 (Figure 1D, magnification ×200) as well as keratin 7 in both the epithelial and spindle cell component.
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