Abstract
Since the outbreak of coronavirus disease 2019 (COVID-19) was first identified, the world has vehemently worked to develop treatments and vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at an unprecedented speed. Few of the repositioned drugs for COVID-19 have shown that they were efficacious and safe. In contrast, a couple of vaccines against SARS-CoV-2 will be ready for mass rollout early next year. Despite successful vaccine development for COVID-19, the world will face a whole new set of challenges including scale-up manufacturing, cold-chain logistics, long-term safety, and low vaccine acceptance. We highlighted the importance of knowledge sharing and collaboration to find innovative answers to these challenges and to prepare for newly emerging viruses.
Highlights
The outbreak of coronavirus disease 2019 (COVID-19) caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which was first reported in Wuhan City, Hubei Province, China, on 31 December 2019, has spread over the world with an unparalleled speed [1,2]
The disease is so transmissible that the number of cases and deaths rose rapidly across borders, which prompted the World Health Organization (WHO) to declare the COVID-19 outbreak to be a global pandemic on 11 March 2020
WHO have supported remdesivir, lopinavir/ritonavir, and chloroquine/hydroxychloroquine for their repositioning potentials for COVID-19, which we describe below in detail [18]
Summary
The outbreak of coronavirus disease 2019 (COVID-19) caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which was first reported in Wuhan City, Hubei Province, China, on 31 December 2019, has spread over the world with an unparalleled speed [1,2]. The disease is so transmissible that the number of cases and deaths rose rapidly across borders, which prompted the World Health Organization (WHO) to declare the COVID-19 outbreak to be a global pandemic on 11 March 2020. Humankind will learn important lessons from handling the global pandemic at this scale, which will allow us to be better prepared for the future public health crises. We stressed the importance of innovative, well-coordinated, long-term research to prepare for future public health crises. To better achieve those objectives, we first briefly described the characteristics of the coronavirus
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