Abstract
Keratoconus is a common non-inflammatory, bilateral progressive corneal dilatation disease, often leading to progressive thinning of the corneal stromal layer, the central region of the cornea is conical, clinical manifestations of high myopia and irregular astigmatism, The normal life of the patient is greatly inconvenient. Therefore, timely and effective treatment is extremely important to improve the visual quality of patients and their physical and mental health. In the early stage of the patient, vision correction can be performed by wearing a frame mirror or a contact lens; as the lesion progresses, the former is insufficient for correction, and corneal stroma implantation, corneal collagen cross-linking, and keratoplasty are feasible. Numerous studies have confirmed that this treatment can effectively improve and maintain the visual quality of patients. In recent years, new treatment methods such as matrix regeneration, matrix lens transplantation and scleral mirror have gradually become research hotspots at home and abroad. This article reviews the current major treatments for keratoconus and its new developments.
Highlights
The keratoconus is a corneal dilatation disease characterized by progressive thinning of the corneal stroma and conical protrusion in front of the cornea
The keratoconus usually begins in adolescence, is common in 15-25 years old, and gradually stabilizes when it is more than 40 years old
The results show that the degree of endothelial damage of femtosecond laser Deep anterior lamellar keratoplasty (DALK) is lower than that of femtosecond laser PKP
Summary
The keratoconus is a corneal dilatation disease characterized by progressive thinning of the corneal stroma and conical protrusion in front of the cornea. The main clinical manifestations are progressive deepening of myopia and irregular astigmatism, with varying degrees of corrected visual acuity. [1,2] studies have shown that patients with pre-refractive surgery have a prevalence of up to 5%. Non-surgical treatment methods mainly include frame mirror and contact lens. The main surgical methods include corneal stroma implantation, corneal transplantation and corneal collagen cross-linking. New treatments such as matrix regeneration, matrix lens transplantation, and scleral mirror have been intensively studied. This article aims to provide a brief overview of the advantages and disadvantages of various treatments in order to bring better treatment to patients with keratoconus
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