Abstract
Neuropixels technology has revolutionized neuroscience research by allowing scientists to obtain physiological firing data from single neurons in the central nervous system with unprecedented temporal and spatial resolution. While the technology is already highly advanced, researchers continue to work on improving it further. In this article, the authors summarize several current studies on improvements and applications of Neuropixels probes. This technology is used to capture the characteristic waveforms of neurons in different brain regions, record particular types of neurons, and acquire detailed data. The improvement of the Neuropixels is the AMIE, which solves the problem of implanting the device in unrestrained mice and recycling, enriching the electrodes and the recording sites on each Neuropixels device. By discussion and investigation, the current conduct and some refinements of the Neuropixels are demonstrated in this brief review. However, fragility and ethical problems are still inevitable obstacles of Neuropixels, and their potential harm to human beings still deserves attention.
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