Abstract

Biotechnologies have been an integral part of improvements in animal genetics, nutrition and health over the past century. Many biotechnologies have become fundamental components of efficient livestock production systems. The genetic improvements that have been enabled by biotechnologies have dramatically decreased the environmental footprint of animal protein production in many parts of the world, and continued innovation is required to address the projected increase in demand for animal products in the future. Breeding programs increasingly utilize a combination of advanced reproductive technologies and genomic tools to accelerate the rate of genetic gain by manipulating components of the breeder’s equation. The use of these biotechnologies and breeding methods has met with little public opposition. In contrast, the use of modern biotechnologies, defined as those that employ the use of in vitro nucleic acid techniques, have been highly controversial, especially those involving the use of genetic engineering. This modern biotechnology distinction is somewhat arbitrary as there are a number of biotechnologies that involve the use of in vitro processes, and many result in genetic modifications that are indistinguishable from the naturally-occurring variation that is the driver of both traditional breeding programs and evolution. A number of useful traits including disease resistance and animal welfare traits have been successfully introduced into various livestock species using both genetic engineering and gene editing techniques. Ultimately these techniques complement the genetic improvement that can be accomplished using traditional selection techniques and, if judged acceptable, offer an opportunity to synergistically accelerate genetic improvement in food animal species.

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