The CryoLife O’Brien stentless porcine aortic bioprosthesis: 5-year follow-up

Abstract

Background. Mortality, morbidity, complication rates, and echo hemodynamic results using the Cryolife O’Brien stentless aortic bioprosthesis over a 5-year period are reported. Methods. The stentless valve was implanted in 97 conscecutive patients, 54 male and 43 female, mean age 70.9 ± 6.5 years. All patients underwent preoperative, discharge (early study), 6-month (intermediate study), and late (18.3 ± 10.4 months) echocardiography. Results. The actuarial 5-year survival rate was 93.9% ± 3%. Aortic regurgitation was absent in 95.5%, mild in 3.4%, and moderate in 1.1%. Peak and mean systolic gradients were significantly lower at discharge ( p < 0.001) and at the 6-month follow-up ( p < 0.001) but did not significantly fall further at the late study ( p = NS). The effective orifice area index at discharge ( p < 0.001) and at 6 months ( p < 0.001) differed significantly from preoperative values, but variations at late study were not significant ( p = NS). Left ventricular mass index decreased early postoperatively ( p < 0.001) and at 6-month assessment ( p < 0.001) with a further significant reduction at late echocardiography ( p = 0.04). Conclusions. The 5-year results of this stentless valve showed a low rate of valve-related complications with excellent hemodynamic performance in all valve sizes.