The Cross-sectional Effect Of Abnormal Glucose Metabolism On Balance Ability, Muscle Strength, And Body Compositionin Men

Abstract

PURPOSE: To investigate the association between balance ability, muscle strength, and body composition, and fasting blood glucose METHODS: 1) Subjects: 2693 men (aged 19-73 years old) were recruited from three health management central of hospitals in China, without any diagnosed diseases other than diabetes. 2) Measurements: People’s grip strength was measured 3 times in dominant hand in a standing position and read the highest value; balance ability was measured by one-leg standing time with both eye-closed; body composition was measured by BIA; fasting venous blood was taken for blood glucose test. All subjects were divided into normal blood glucose group (Normal: < 6.1 mmol/L), impaired fasting glucose group (IFG: 6.1-7.0 mmol/L), and diabetes group (DM: ≥7.0 mmol/L). 3) Statistics: Multivariate analysis of variance was used for comparison among groups; Pearson test was used for correction analysis; the significance level (α) for hypothesis testing was set to 0.05. RESULTS: Normal glucose men were significantly younger than those in the IFG and DM group (38.76±9.45 vs. 44.57±9.09 vs. 45.87±4.79 yrs, P < 0.05). Normal glucose men had significantly lower body weight and lower percent body fat than those in the IFG and DM group (BW: 70.70±11.29 vs. 75.68±10.40 vs. 77.23±11.66 kg, P < 0.05; BF%:15.55±6.38 vs. 18.97±5.82 vs. 25.12±5.62, P < 0.05). Balance ability, relative grip strength, and muscle percentage [(body muscle/ body weight)*100) were different in three groups (P < 0.05). There were inverse linear associations between incremental level of blood glucose and lower values of balance ability, relative grip strength, and muscle percentage (r =-0.067 , r =-0.158, r =-0.171 , P < 0.05 for each). After adjusted age, the blood glucose level was still correlated with balance ability (r =-0.035 , P=0.068). CONCLUSIONS:The men’s balance ability decreases with the increase of blood glucose level. There are inverse linear associations between muscle strength and muscle percentage and blood glucose level.Acknowledgement:1) China Health Foundation Project “Multi-Center Application Research on Fitness Fitness Test and Exercise Management” (CHPF2014-FITEX); 2) National Key Research and Development Program Major Prevention and Control Research on Chronic Non-communicable Diseases (2016YFC1300202).