Abstract

BackgroundTo evaluate the cost of diabetes related micro- and macrovascular complications in Iranian people with type 2 diabetes mellitus.MethodsIn routine clinical practice, people with type 2 diabetes mellitus were assessed for 10 years at a diabetes care center. The type of medications and clinical data were extracted from patients’ documents. Mortality rate and the incidence of micro- and macrovascular complications recorded in patients’ documents were analyzed. Cost analysis was comprised of 1) para clinic costs as well as laboratory, medications, clinical visits and nonmedical costs 2) inpatient costs as well as hospital admission costs, disability, and mortality costs.ResultsFrom 1562 people with type 2 diabetes mellitus, a total of 1000 patients with mean duration disease of 11.2 years, who had completed information in their documents, were studied. All people were free from complications at baseline. Mean cumulative incidence of diabetes-related complications over 10 years were 10.9 ± 3.5%, 8.0 ± 3.1%, 4.6 ± 1.7%, 9.1 ± 3.6% and 2.3 ± 0.9% for peripheral neuropathy and diabetic foot ulcer, nephropathy, ophthalmic complications, cardiovascular disease and death, respectively. People with better glycemic control had less complication and also related expenditures. Average para clinic cost per patient was 393.6 ± 47.8 and average inpatient cost per patient was 1520.7 ± 104.5 USD.ConclusionsOur findings demonstrate considerable incidence of diabetes chronic complications and also high health care expenditure for related complications among our patients. As the number of people with diabetes continues to rise, early detection of the disease and implementation of timely and appropriate therapeutic strategies could decrease the burden of diabetes chronic complications and also huge related expenditures.

Highlights

  • To evaluate the cost of diabetes related micro- and macrovascular complications in Iranian people with type 2 diabetes mellitus

  • Results of the present study indicated that diabetes chronic complications, and total healthcare costs were affected by age, gender and glycemic control as higher incidence of complications and health care expenditure were observed in the aged males (>60 years), and people with poor glycemic control (A1C >8.5%)

  • We found that middle aged people (40–60 years old) had more disability costs due to diabetes health problems which emphasis the importance of attention to people with more productivity in the society

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Summary

Introduction

To evaluate the cost of diabetes related micro- and macrovascular complications in Iranian people with type 2 diabetes mellitus. The prevalence of type 2 diabetes mellitus is rising dramatically worldwide, mostly in developing countries. It is associated with highly cost-demanding complications [1,2,3]. In 2011, the number of people with diabetes mellitus was estimated to be 366 million. The data represented by the National Survey of Risk Factors for Non-Communicable Diseases of Iran indicate that 7.7% of adults younger than 65 years had type 2 diabetes in 2008 [1]. Glycemic control is the main step of treatment in people with type 2

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