Abstract
Objective To explore the depression status and its con-elation with quality of life(QOL) in patients receiving methadone maintenance treatment (MMT). Methods 120 patients treated with MMT were assessed with Quality of Life Scale for Drug Addicts (QOL-DA) and Beck Depression Inventory (BDI-21). Results More than 41 years old group's QOL-DA physical function domain(28.79 ±8.53) was significantly lower than 31～40 years old group (33.52 ± 6. 73) (P= 0.003). According to BDI-21 score ,55% patients receiving MMT were classified as moderate or severe depression. QOL-DA scores decreased in order of the depression severity classified as no depression group,mild depression group,moderate depression group and severe depression group according to the BDI-21 score,and the difference between the groups were significant statistically (P<0.01). There was significantly negative correlation between BDI-21 score and QOL-DA score (P<0.01). Conclusion Depression is very common in opioid dependent patients receiving MMT and decreases their quality of life,so it is important to enhance depression intervention or treatment in MMT clinics. Key words: Methadone maintenance treatment; Opioid dependent; Quality of life; Depression
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