Abstract
The rate of oxygen uptake of leucocytes from patients with different degrees of thyroid activity was studied, and it was shown that there is a direct relationship between the oxygen uptake of leucocytes and the BMR of the patient. The leucocytes from hyperthyroid patients had an oxygen uptake of 0·185±0·037 µM./hr./107 cells. Leucocytes from euthyroid people had an oxygen uptake of 0·119±0·021 µM./hr./107 cells. The leucocytes from myxœdematous patients had an oxygen uptake of 0·083±0·016 µM./hr./107 cells.The effect of treatment on the oxygen consumption of leucocytes from three patients with myxœdema and three with hyperthyroidism was then investigated. The hyperthyroid patients were treated with 131I and after therapy there was a decrease in the oxygen consumption of the leucocytes. In the three patients with myxœdema, the oxygen consumption of the leucocytes increased after thyroxine therapy.
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