The Correlation of Anthropometric, the Estradiol Level and Obesity in Perimenopausal and Menopausal Saudi Women

Abstract

In this study we assess the age-specific variation anthropometric measurements, the estradiol hormone, and Body Mass Index variation levels among perimenopausal and menopausal Saudi women. We conducted this study on 41 healthy women aged 40 to 75 and divided them into two groups. The group included 25 perimenopausal women (<50 Years), and 16 menopausal women (>50 Years) were examined. Demographic data were recorded, and blood serum samples were drawn in plain and in A serum separator tube was used to estimate estrogens in the serum. We found a significant difference between WHR in perimenopausal women (<50 Years) and menopausal women (>50 Years) subjects (mean ± SD WHR: 0.9040 ±0.0351 vs.0.8688 ±0.0602, p=0.0181). There was also a significant difference in circulating E2 level, where the osteoporotic patients had a lower circulating E2 than non-menopausal women (>50 Years) (mean ± SD E2: 81.6000 ± 54.7456 vs. 48.5000 ± 20.0300 pg/mL, p=0.0002). Our conclusion showed women with the highest levels of estradiol hormones had the highest WHRs, while women with low estradiol showed the lowest WHRs. However, we need more studies involving Saudi women with a larger sample population and different geographic locations are recommended to have more complete data on menopausal women.