Abstract
Introduction. Circulating platelets play an essential role in the immune system and furthermore in tumor development and proliferation. Therefore, the correlation between different neoplasia and the number of platelets has been widely studied. The aim of the current paper is to investigate the correlation ship between platelet number and tumoral endometrial transformation. Material and methods. Between January 2022 and June 2022 22 patients with endometrial hyperplasia or endometrial cancer were submitted to surgery. The serum levels of platelets were determined and compared to those reported in a similar group of patients in whom the endometrial lining was normal. Results. Patients diagnosed with endometrial cancer presented a significantly higher number of platelets as well as a significantly higher platelet volume when compared to patients diagnosed with endometrial hyperplasia and respectively to those in whom a normal endometrial lining was found. Conclusions. The serum number of platelets and their volume seem to be positively correlated with the aggressivity of the tumoral transformation of the endometrial lining and should be therefore considered as part of the elements which should be analyzed when discussing the best therapeutic option in such patients.
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