The Correlation between the Characteristic of Reflux Based on 24 Hours-Multichannel Intraluminal ImpedancePh Monitoring with the Quality of Life of Refractory Laryngopharyngeal Reflux Patients

Abstract

The evaluation of the quality of life of LPR patients is crucial to assess the success of medical therapy and help with diagnosis. Assessment of life quality of patients with refsractory LPR by using the selected LPR HRQL questionnaire because it is more practical to use, easy to set scoring and analyze data. Objective: This study aims at investigating the reflux characteristic and the correlation with refractory Laryngopharyngeal Reflux (LPR) patients quality of life. Method: The examination is performed on ten refractory LPR patients using 24hour - MultichanneI Intraluminal Impedance pH monitoring, then grouped according to the characteristics of the reflux acid, non-acidic, and mixed. Furthermore, the assessment of life quality by using LPR-HRQL questionnaire. Data analysis using Chi-Square and Spearman’s Rho methods. Results: The sampleLPR refractory is generally female (66.7%), while males (33.3%). Mixed reflux type as much as 44.4%, then 33.3% acid reflux, and a non-acidic reflux 22.2%. LPR occurrence of majority at upright position (66.7%). Non-acid reflux patients consistently for all symptoms/complaints, indicating quality of life is disrupted based on questionnaires found in the LPR-HRQL (100%). Conclusion: The quality of life of non-acid reflux patients is more disturbed than the acidic and mixed reflux group.