Abstract

Urticaria and angioedema are among the commonly encountered clinical conditions in the emergency department (ED). The severity of these conditions ranges from a simple rash to life threatening uvular edema. Recently, several studies on determining the relationship between the coagulation and inflammation markers with the acute exacerbation and severity especially on chronic urticaria patients have been published. Studies in the literature were primarily focused on patients with chronic urticaria and there appears to be no study on evaluating the level of those markers in patients with acute urticaria or angioedema. We aimed to evaluate the correlation between the coagulation and inflammatory markers with the acute exacerbation and severity of illness in patients presenting to our ED with acute urticaria or angioedema.

Highlights

  • Urticaria and angioedema are among the commonly encountered clinical conditions in the emergency department (ED)

  • We aimed to evaluate the correlation between the coagulation and inflammatory markers with the acute exacerbation and severity of illness in patients presenting to our ED with acute urticaria or angioedema

  • In patients for which acute urticaria or angioedema were diagnosed after the initial anamnesis and physical examination, an intravenous line was started and blood samples for microCRP, fibrinogen and D-dimer were collected in 4 ml citrated and 2 ml biochemistry tubes

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Summary

Introduction

Urticaria and angioedema are among the commonly encountered clinical conditions in the emergency department (ED). The severity of these conditions ranges from a simple rash to life threatening uvular edema [1]. Several studies on determining the relationship between the coagulation and inflammation markers with the acute exacerbation and severity especially on chronic urticaria patients have been published. Studies in the literature were primarily focused on patients with chronic urticaria and there appears to be no study on evaluating the level of those markers in patients with acute urticaria or angioedema. We aimed to evaluate the correlation between the coagulation and inflammatory markers with the acute exacerbation and severity of illness in patients presenting to our ED with acute urticaria or angioedema

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