The correlation between body mass index and prostatic-related parameters in men 40 years or older in Zhengzhou

Abstract

Purpose To understand the relationship between body mass index (BMI), age, prostate volume (PV), prostate-specific antigen (PSA), International Prostate Symptom Score (IPSS) and quality of life (QoL) in Zhengzhou. Materials and methods In the cross-sectional study, men living in Zhengzhou were invited to participate in this study. Men who were 40 years or older were subjected to the IPSS and related examination. A total of 1360 participants were included. Body mass index < 18.5 kg/m2 was determined as underweight, 18.5–24.99 kg/m2 normal, 25–29.99 kg/m2 overweight, and ≥30 kg/m2 obese. Results The mean BMI was 24.92 ± 3.37 kg/m2. The mean PSA was 1.06 ± 0.85 ng/mL. The mean PV was 20.10 ± 9.96 mL. The mean age was 62.72 ± 11.03 years. The mean IPSS was 5.87 ± 3.48 scores. The mean QoL was 2.33 ± 1.28 scores. PSA showed a significant tendency to decrease with increasing BMI (r = −0.061, p = 0.018, p trend = 0.037). The same with age (r = –0.109, p < .001; p trend = .045). But the result suggested that both IPSS and QoL were positively correlated with BMI (r = 0.120, p < .001, p trend < .001; r = 0.083, p = .001, p trend = .021, respectively). PV increased with increasing BMI (r = 0.110, p < .001, p trend = 0.045 ). Conclusions Age, PSA decreased with increasing BMI. But larger PV, IPSS, and QoL were associated with higher BMI.