Abstract

Background: Oral cancer (OC) in Bangladesh accounts for about 40% of all cancers of the body. Since the majority of human cancers are derived from epithelial cell changes in blood group antigens, it is an important aspect of human malignancies. Recently, it has been suggested that the ABO blood group may affect the development of oral cancer. The aim of this study was to evaluate the association between ABO blood group type and OC. Material & Methods: This observational study was conducted in the Labaid Cancer Hospital and Super Speciality Center, Dhaka, Bangladesh during the period from April 2021 to January 2023. Results: In total 110 patients from both male and female patient who were histopathologically diagnosed of oral cancer were included in the study. In our study we found the most common age group affected in OC was 51-60 years and more in males. The most common site affected by OC was buccal mucosa. Blood group A patients were more common in OC. Conclusion: The presence of antigen A on cells may increase the risk of oral cancer according to our study, while blood type O was less common in these patients.

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