Abstract
Systemic disease often results in corneal signs that are easily observable by means of bio-microscopy. Optometry is in a unique position to detect the corneal manifestations of systemic disease. This review presents corneal signs of various systemic diseases. The list is not com-plete but the review rather attempts to empha-size the importance of detection, and referral, of systemic diseases.
Highlights
There are numerous ocular signs and symptoms of systemic disease[1]
Vascular systemic diseases that might result in ocular signs include diabetes, hypertension and hyperlipidemia, while autoimmune diseases could include Reiter’s syndrome, rheumatoid arthritis and systemic lupus erythramatosis
While many of the diseases mentioned above produce changes in the crystalline lens, the retina, extra-ocular muscles and other structures in and around the eye, this review is going to be limited to the corneal manifestations of systemic disease
Summary
There are numerous ocular signs and symptoms of systemic disease[1]. Vascular systemic diseases that might result in ocular signs include diabetes, hypertension and hyperlipidemia, while autoimmune diseases could include Reiter’s syndrome, rheumatoid arthritis and systemic lupus erythramatosis. While many of the diseases mentioned above produce changes in the crystalline lens, the retina, extra-ocular muscles and other structures in and around the eye, this review is going to be limited to the corneal manifestations of systemic disease. Corneal manifestations of metabolic disorders occur when a systemic metabolic process results in an accumulation of abnormal substances in the cornea[3].
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