Abstract
1. The common dogfish, Mustelus canis, has a dark phase and a light one due to the expansion and the contraction of its dermal melanophores.2. The dark phase is induced by pituitary secretions carried from the pituitary gland to the melanophores by the blood and lymph as described by Lundstrom and Bard.3. The light phase is induced through the action of contracting nerves, and is not merely the result of the absence of pituitary secretions.4. The expanding hormone is water-soluble. The contracting one, if there be such, is apparently not water-soluble.5. The dogfish is remarkable as the first form to be described in which the cutting of nerves induces a contraction of the melanophores and a consequent lightening of the skin.
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