Abstract

Human mixed saliva and secretions from the labial, palatine, parotid, submandibular and combined sublingual-submandibular glands were collected after pilocarpine stimulation from five subjects with different blood groups. The protein concentration of the minor gland secretions was in the same order of magnitude as in the other samples tested. The secretions of minor glands had high concentrations of total carbohydrate and fucose, but their relative contribution to mixed saliva could not be assessed because secretions of major glands had concentrations in the same range as mixed saliva. The secretions of minor glands had high concentrations of substances with blood-group specificity (A, B, Le a, Le b) and virus-haemagglutination inhibition activity. They appeared to contribute as much as the combined major gland secretions to the content of these substances in mixed saliva. The distribution of these substances indicated that different regions of the oral cavity may be exposed to fluids with different chemical characteristics.

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