Abstract
The initial cutaneous vasodilatory response to local skin heating is greater in the forearm than in the leg (1). While the initial vasodilatation of the forearm in response to local heating is primarily dependent on sensory nerves (2), their role in the leg is unknown. We compared the contribution of sensory nerves in regulating the cutaneous vasodilatory response of the forearm and leg to local heating using a local anaesthetic (EMLA) cream.
Highlights
The initial cutaneous vasodilatory response to local skin heating is greater in the forearm than in the leg (1)
Data are presented as cutaneous vascular conductance (CVC), calculated as laser-Doppler flux divided by mean arterial pressure from auscultation, and expressed as a percentage of maximal CVC
CVC during the initial vasodilatation to local heating was smaller in the leg (47(9) %max) compared to the forearm (62(7) %max, p = 0.012)
Summary
The initial cutaneous vasodilatory response to local skin heating is greater in the forearm than in the leg (1). While the initial vasodilatation of the forearm in response to local heating is primarily dependent on sensory nerves (2), their role in the leg is unknown. We compared the contribution of sensory nerves in regulating the cutaneous vasodilatory response of the forearm and leg to local heating using a local anaesthetic (EMLA) cream
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