THE CONTRIBUTION OF “In Vitro” SKELETAL MUSCLE FIBER BIOCHEMICAL TIMING ANALYSIS IN THE UNDERSTANDING OF ELECTROMYOGRAPHIC SPECTRUM

Abstract

Introduction“In vivo” electromyography usually reports a frequency domain muscle activity in a broad Hertz spectrum that ranges from 1 Hz to 500 Hz. However, when the contiguous nicotinic biochemical events in rhabdomyocytes type Ia, IIa and IIb are timed “in vitro”, and then converted to Hertz. A reduced electromyographic frequency domain is obtained.Materials and MethodsGoogle Scholar databases and National Library of Medicine, were searched for articles published from 1990 to 2019 containing times of kynetic cell signalig in raddomiocytes type Ia IIa and IIB join terms like 1) “Title (TI)= ‘Time Acetylcholine exocytosis’ AND ‘Time Activation nicotinic receptor’ AND ‘Time Depolarization of sarcolemma’ AND ‘Excitation–contraction coupling’ AND ‘Time depolarization T‐tubule” AND ‘Cross‐bridge cycle’. The inclusion criteria were that each study involving a types of striated muscle fiber “In vitro” as an objective measure interaction Acetylcholine‐Nicotinic Recepptor and cascade cell signaling to evaluating speed of despolarizatig and every physiological contraction subphases of contraction. Once every time of physiological event of contraction was found, the time was added and then the mathematical inverse of the period in seconds was converted to frequency in Hertz.Results“In vitro” the total time events of contraction summed to striated muscle fiber Type IA were 3,33 ms; Fibers Type IIA were 6,81 ms; and Fibers Type IIB were 7,41 ms. Times that converted to Hertz show fiber type Ia, IIa IIb with 3,03 Hz, 1,46 Hz, 1,34 HzConclusionsThe electromiographic Hertz domain is made of a series of “noise” such as the different extracellular events that occur between inferior motor neurons and sarcolemmas. The present work aims to rationalize the obtained “in vitro” frequency spectrum values of 3,03 Hz, 1,46 Hz, 1,34 Hz for type Ia, IIa and IIb respectively.Support or Funding InformationUNIVERSIDAD DE LA SABANA