The contribution of adrenal and gonadal androgens to the growth in height of adolescent males.

Abstract

Gonadal androgens are known to regulate the rate of growth in height during adolescence, particularly in males, but little is known of the role of adrenal androgens in this process. In a prospective multiple regression model we show that both adrenal and gonadal androgens contribute to the increasing rate of growth in height prior to peak height velocity and the decreasing rate of height growth in later adolescence. Since adrenal androgen secretion begins in mid-childhood, long before gonadal maturation and the secretion of testicular androgens, these findings may prove helpful in explaining population variation in adolescent growth.