Abstract

soap, and helminth treatment could prevent most of these AEs. Contraception (FP) was provided and there were no pregancies. In the TasP trial, the majority of participants will have a spouse. Voluntary HIV Testing and Counseling (VTC) is a trial procedure and Couples’ VCT (CVCT) should also be, as recommended by WHO. The protocol refers to ‘family testing’ but this is not a prevention strategy. CVCT is associated with a reduction in new HIV infections and should be explicitly included in protocols and procedures. HIA for TasP should be compared with HIA CVCT, MC, and FP. Conclusions: Both trials and participants would benefit from low-cost screening and treatment services for endemic diseases such as bed nets, routine deworming, soap and chlorine as well as provision of contraceptives. TasP trials should analyze costs and have a rationale for testing interventions with HIA >PPP. Excluding locally affordable HIV prevention services including CVCT from trial SOC is unethical.

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