Abstract
Following a suspected case of hantavirus in a patientsuffering from acute kidney injury, rodents fromthe patient’s property in Yorkshire and the Humber,United Kingdom (UK) were screened for hantaviruses.Hantavirus RNA was detected via RT-PCR in two Rattusnorvegicus. Complete sequencing and phylogeneticanalysis established the virus as a Seoul hantavirus,which we have provisionally designated as strainHumber. This is the first hantavirus isolated from wildrodents in the UK and confirms the presence of a pathogenicSeoul virus in Europe.
Highlights
Rapid communicationsThe continued emergence of hantaviruses: isolation of a Seoul virus implicated in human disease, United Kingdom, October 2012
Following a suspected case of hantavirus in a patient suffering from acute kidney injury, rodents from the patient’s property in Yorkshire and the Humber, United Kingdom (UK) were screened for hantaviruses
In January 2012, as part of routine diagnostic services, the Rare and Imported Pathogens Laboratory (RIPL) at the Health Protection Agency (HPA) Porton, detected a suspected case of hantavirus infection in a patient diagnosed with acute kidney injury (AKI) from Yorkshire and the Humber, United Kingdom (UK)
Summary
The continued emergence of hantaviruses: isolation of a Seoul virus implicated in human disease, United Kingdom, October 2012. Following a suspected case of hantavirus in a patient suffering from acute kidney injury, rodents from the patient’s property in Yorkshire and the Humber, United Kingdom (UK) were screened for hantaviruses. Complete sequencing and phylogenetic analysis established the virus as a Seoul hantavirus, which we have provisionally designated as strain Humber. This is the first hantavirus isolated from wild rodents in the UK and confirms the presence of a pathogenic Seoul virus in Europe. In January 2012, as part of routine diagnostic services, the Rare and Imported Pathogens Laboratory (RIPL) at the Health Protection Agency (HPA) Porton, detected a suspected case of hantavirus infection in a patient diagnosed with acute kidney injury (AKI) from Yorkshire and the Humber, United Kingdom (UK). With permission from the patient, trapping of rodents in the vicinity of the family residence and farm was undertaken in February/ March 2012, with the aim of confirming the presence of an aetiological agent in these rodents that might be responsible for the patient’s AKI
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