Abstract

Associations between alcohol consumption and the prevalence of cardiovascular diseases have been the subject of several studies for a long time; however, the presence and nature of any associations still remain unclear. The aim of the study was to analyze the associations between the consumption of alcoholic beverages and the prevalence of cardiovascular diseases in men and women. The data of 12,285 individuals aged 37–66 were used in the analysis. Multiple logistic regression models were utilized to estimate odds ratios and confidence intervals. The multivariable models included several potential confounders including age, education, marital status, body mass index (BMI), physical activity, smoking, coffee consumption, and statin use. The analyses were performed separately for men and women. In the model adjusted for confounders, the consumption from 0.1 to 10.0 g of alcohol/day was related to a lower risk of coronary disease and stroke (p < 0.05), and the consumption from 0.1 to 15.0 g/day was related to a lower risk of hypertension in women (p < 0.05). In men, in the adjusted model, there were no associations between alcohol consumption and the occurrence of hypertension or stroke. The risk of circulatory failure was significantly lower in the group in which participants drank more than 20.0 g of alcohol/day (p < 0.05) compared to nondrinkers. The risk of coronary disease was lower in drinkers at every level of alcohol consumption (p < 0.05) compared to nondrinkers. Alcohol consumption was related to a lower prevalence of cardiovascular diseases (CVD), both in men and women.

Highlights

  • Cardiovascular diseases (CVD) have been the main cause of deaths both in Europe and worldwide for many years [1], and the frequency of cardiovascular diseases (CVD) deaths is higher in men than in women [2]

  • Hypertension was diagnosed in 37.3%, stroke in 1.7%, coronary disease in 9.1%, and circulatory failure in 6.3% of the participants (Table 1)

  • Circulatory failure was more common in women (p < 0.001), whereas strokes were more prevalent in men (p = 0.049)

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Summary

Introduction

Cardiovascular diseases (CVD) have been the main cause of deaths both in Europe and worldwide for many years [1], and the frequency of CVD deaths is higher in men than in women [2]. CVD risk factors include dyslipidemias, abnormal glucose level, diabetes, obesity, malnutrition, low physical activity, tobacco smoking, chronic stress, and excessive alcohol consumption [3,4,5,6,7]. Several reports indicate the beneficial effect of a low intake of alcoholic beverages on the reduction of CDV risk [16,17,18]. Results of some research indicate that the risk of CVD is the lowest with an intake of 2.5–14.9 g/day [13]. There is no consensus as to whether low-risk drinking should be defined in the same way for men and women [19]. The relationship between alcohol consumption and CVD risk in both sexes differs in some studies [12,21,22]

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