Abstract

Endometriosis is a chronic, hormone-dependent,inflammatory disease, characterized by the presence and growth of endometrial tissue outside the uterine cavity and it is associated with chronic pelvic pain and infertility.

Highlights

  • Endometriosis is a chronic, hormone-dependent, inflammatory disease, characterized by the presence and growth of endometrial tissue outside the uterine cavity and it is associated with chronic pelvic pain and infertility [1,2]

  • One caveat is transvaginal ultrasonography, transrectal ultrasound, and MRI, have the potential to facilitate the diagnosis of certain types of endometriosis, an endometrioma or deep infiltrating endometriosis [8]

  • One study found that silent nociceptors account for 50% of all nociceptors in visceral organs and deep somatic tissues and are sensitized by the inflammatory mediator Nerve Growth Factor (NGF) seen in endometriosis peritoneal fluid [27]

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Summary

Summary

We published a manuscript entitled “A Novel, Non-opioid Treatment for Chronic Pelvic Pain in Women with Previously Treated Endometriosis Utilizing Pelvic-Floor Musculature Trigger-Point Injections and Peripheral Nerve Hydrodissection”. There is no cure, traditionally endometriosis symptoms are managed with a combination of hormonal and surgical treatments. This manuscript is a commentary on a unique outpatient neuromusculoskeletal protocol to add to the traditional hormonal and surgical approaches to help improve pain and function in patients with endometriosis. This commentary takes a gastrointestinal and colorectal slant as to how the complex disease process of endometriosis can affect these organ systems and the symptoms that arise when this happens

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