Abstract

In analysis of the human connectome, the connectivity of the human brain is collected from multiple imaging modalities and analyzed using graph theoretical techniques. The dimensionality of human connectivity data is high, and making sense of the complex networks in connectomics requires sophisticated visualization and analysis software. The current availability of software packages to analyze the human connectome is limited. The Connectome Visualization Utility (CVU) is a new software package designed for the visualization and network analysis of human brain networks. CVU complements existing software packages by offering expanded interactive analysis and advanced visualization features, including the automated visualization of networks in three different complementary styles and features the special visualization of scalar graph theoretical properties and modular structure. By decoupling the process of network creation from network visualization and analysis, we ensure that CVU can visualize networks from any imaging modality. CVU offers a graphical user interface, interactive scripting, and represents data uses transparent neuroimaging and matrix-based file types rather than opaque application-specific file formats.

Highlights

  • A foremost aspiration in neuroscience is understanding the connectivity of the human brain

  • We introduce a general-purpose, free, and open source software package written in python specially designed for the visualization of multi-modal human brain networks: the Connectome Visualization Utility (CVU)

  • CVU is an integrated application designed for the interactive visualization of human brain networks

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Summary

Introduction

A foremost aspiration in neuroscience is understanding the connectivity of the human brain. Connectome Visualization Utility Software for Human Brain Networks analysis of this high-dimensional connectivity data presents a challenging problem. The emerging field of connectomics has risen to meet this challenge, leveraging new advances in graph theory to understand human brain function and leading to the development of multi-institution initiatives such as the Human Connectome project [1]. Elegans as well as other complex networks from numerous domains were shown to exhibit small-world organization [3]. Graph theoretical approaches lending new insight to the dynamics of complex networks began to proliferate, including in the study of social networks, the internet, and food webs [4]

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